Michael Gillen Selected Research

lesinurad

1/2019	Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers.
1/2019	Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor.
7/2017	Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide.
7/2017	Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
6/2016	In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters.
1/2016	Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
1/2016	Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study.

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Michael Gillen Research Topics

Disease

16	Gout 01/2019 - 01/2016
10	Hyperuricemia 01/2019 - 01/2017
8	Asthma (Bronchial Asthma) 06/2021 - 05/2008
8	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 11/2008
1	Body Weight (Weight, Body) 01/2018
1	Rheumatoid Arthritis 12/2015
1	Heart Failure 12/2015
1	Chronic Kidney Failure (Chronic Renal Failure) 12/2015
1	Seasonal Allergic Rhinitis (Hay Fever) 10/2002
1	Rhinitis 10/2002

Drug/Important Bio-Agent (IBA)

14	Uric Acid (Urate)IBA 01/2019 - 01/2016
9	verinuradIBA 01/2019 - 01/2017
7	lesinuradIBA 01/2019 - 01/2016
6	Budesonide (Pulmicort)FDA LinkGeneric 01/2020 - 05/2008
6	Xanthine OxidaseIBA 01/2019 - 01/2016
5	Formoterol Fumarate (Oxis)FDA Link 01/2020 - 11/2008
4	SuspensionsIBA 06/2021 - 01/2018
4	Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric 01/2021 - 01/2018
3	budesonide-glycopyrrolate-formoterol fumarate drug combinationIBA 10/2020 - 01/2020
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 05/2008
2	Febuxostat FDA Link 01/2018 - 01/2018
2	Colchicine FDA LinkGeneric 01/2018 - 07/2017
2	Allopurinol (Remid)FDA LinkGeneric 01/2018 - 01/2018
1	Albuterol (Salbutamol)FDA LinkGeneric 06/2021
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2021
1	Muscarinic AntagonistsIBA 01/2020
1	coumarinIBA 01/2019
1	AnticoagulantsIBA 01/2019
1	AntacidsIBA 01/2019
1	Warfarin (Coumadin)FDA LinkGeneric 01/2019
1	BenzbromaroneIBA 01/2018
1	Naproxen (Naprosyn)FDA LinkGeneric 07/2017
1	Indomethacin (Indometacin)FDA LinkGeneric 07/2017
1	AZD1981IBA 01/2017
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2017
1	Digoxin (Digitek)FDA LinkGeneric 12/2015
1	Syk KinaseIBA 12/2015
1	fostamatinibIBA 12/2015
1	Bronchodilator Agents (Bronchodilators)IBA 03/2014
1	Methacholine Chloride (Methacholine)FDA Link 04/2011
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 05/2008
1	ebastine (Kestin)IBA 10/2002
1	AllergensIBA 10/2002

Therapy/Procedure

8	Metered Dose Inhalers (Metered Dose Inhaler) 10/2020 - 11/2008
3	Therapeutics 10/2020 - 11/2008
3	Dry Powder Inhalers 01/2020 - 05/2008
1	Inhalation Spacers 01/2018